Ledipasvir and sofosbuvir are used together in the treatment of chronic hepatitis C virus (HCV) infection. The fixed-dose combo of LEDIPASVIR & SOFOSBUVIR is an effectual way of treating chronic hepatitis C (HCV) infection of genotypes 1, 4, 5 and 6.
Ribavirin, also referred to as tribavirin, is an important antiviral medication for treating HCV. For HCV patients with genotype 1A and not having a cirrhotic liver, Ledipasvir & Sofosbuvir is used without ribavirin.
Ledipasvir & Sofosbuvir was the first FDA-approved interferon and ribavirin-free regimen for treating hepatitis C. Furthermore, the duo is a direct-acting antiviral regimen.
What is LEDIPASVIR?
HCV NS5A is a viral phosphoprotein. It plays the key role in viral assembly, replication and secretion. Ledipasvir acts as a potent inhibitor of HCV NS5A.
What is SOFOSBUVIR?
Hepatitis C Virus NS5B polymerase is the key enzyme responsible for mediating HCV RNA replication. Sofosbuvir is a nucleotide analog inhibitor of HCV NS5B.
In its triphosphate form, sofosbuvir imitates the natural cellular uridine nucleotide. Hence, it is assimilated by the HCV RNA polymerase, NS5B, into the extending RNA primer strand. This ultimately leads to a viral chain termination.
Both Ledipasvir and sofosbuvir are antiviral medications. Both of these medications work by lessening the amount of hepatitis C virus in the body.
These medications achieve so by eliminating the hepatitis C virus gradually from the blood. The specific period of time required for doing so depends on the intensity of the HCV infection.
Typically, dosage for the Ledipasvir & Sofosbuvir in treating HCV infection is limited to single-pill for a single-day. Nonetheless, this might vary in some cases.
Several clinical trials and observational studies define the effectiveness of the Ledipasvir & Sofosbuvir combination in fighting HCV. In most of them, the duo has proved to provide 12-week results of other popular HCV treatments in just an 8-week regimen.
When overdosed, Ledipasvir and sofosbuvir are known to cause two health issues, which are
Popular LEDIPASVIR & SOFOSBUVIR Medications
Here are some of the popular LEDIPASVIR & SOFOSBUVIR medicines available in the market:
How To Order Medicines
To buy LEDIPASVIR & SOFOSBUVIR Medicines in Russia, China, Philippines, US fill out the form on the website at chawlamedicos.com. Our team will contact you after filling out the form to discuss the details of the purchase. You can also contact us by phone: + 91-9999098733 , by e-mail firstname.lastname@example.org or you can directly visit our site www.chawlamedicos.com
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